Chimpanzees and humans harbour compositionally similar gut enterotypes. in Handbook of Paleoanthropology (eds Henke, W. This study is a comprehensive examination of the evidence concerning the existence of enterotypes. Enterotypes in the landscape of gut microbial community composition. Categorization of the gut microbiota: enterotypes or gradients? Nat. Rapid changes in the gut microbiome during human evolution. Destabilization of the gut microbiome marks the end-stage of simian immunodeficiency virus infection in wild chimpanzees. SIV-induced instability of the chimpanzee gut microbiome. The contribution of long-term research at Gombe National Park to chimpanzee conservation. Personality in the chimpanzees of Gombe National Park. High-resolution comparative analysis of great ape genomes. Generation times in wild chimpanzees and gorillas suggest earlier divergence times in great ape and human evolution. The evolutionary context of the first hominins. Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.

This study identifies heritable members of the human microbiome and the genetic factors influencing the abundance of certain bacterial taxa. Genetic determinants of the gut microbiome in UK twins. The effect of host genetics on the gut microbiome. Host genetic variation impacts microbiome composition across human body sites. This analysis shows that many publications reporting an association between microbiome composition and obesity were baseless.īlekhman, R. Looking for a signal in the noise: revisiting obesity and the microbiome. Our gut microbiome: the evolving inner self. Tiny microbes, enormous impacts: what matters in gut microbiome studies? Genome Biol. Xenobiotics shape the physiology and gene expression of the active human gut microbiome. Succession of microbial consortia in the developing infant gut microbiome. Seasonal cycling in the gut microbiome of the Hadza hunter-gatherers of Tanzania. The microbiome of uncontacted Amerindians. This paper serves as the foundational survey of the variation of the human gut microbiome across populations.Ĭlemente, J. Human gut microbiome viewed across age and geography. The relationship between the human genome and microbiome comes into view. Linking long-term dietary patterns with gut microbial enterotypes. This pioneering study shows that dietary differences in African and European children were associated with differences in the composition of the gut microbiome. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa.

Meta-analysis of gut microbiome studies identifies disease-specific and shared responses. This commentary posits that the reduction in microorganisms in contemporary human populations is responsible for increases in autoimmune, metabolic and neurological disorders.ĭuvallet, C., Gibbons, S. The theory of disappearing microbiota and the epidemics of chronic diseases. Correcting for batch effects in case-control microbiome studies. The human gut microbiome: from association to modulation. Population-level analysis of gut microbiome variation. Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity. This report demonstrates that human individuals assigned to different dietary groups diverged in the compositions of their gut microbiomes. Diet rapidly and reproducibly alters the human gut microbiome. in Physiology of the Gastrointestinal Tract 6th edn (eds Said, H. The gut microbiota - masters of host development and physiology. A review of metabolic potential of human gut microbiome in human nutrition. Current understanding of the human microbiome. The intestinal microbiome in early life: health and disease. The human microbiome: at the interface of health and disease.

Ancestral chimpanzee diet